Biointelligence is an organization that works as an interface between academia and the industry. We believe in providing practical education in order to prepare an individual with the technical aspects to establish himself in the industry.

 

Bioinformatics Tools :

Bioinformatics tools are used widely in the biosciences industry for data retrieval and comparative analysis, the students should be well acquainted by these tools in order to settle themselves properly to the industry . These tools are a must for all the sectors in the biosciences fields .

 

Application of Bioinformatics in various disciplines biosciences?

The computational tools are equally important to wet lab techniques done for the validation of the result . These tools are widely used in the fields of biotechnology, microbiology , life sciences , biochemistry , botany zoology , etc . Perfection on these tools leads to more accurate result as well as are a MUST to enter into the industry .

 

Job Prospects in the Industry ?

The industry needs highly technical candidates in the sectors of Pharmacy , Bioinformatics /IT ,KPO ,CRO sectors . To enter into these fields one has to be very efficient in the wet lab as well as dry lab skills.
If an individual wants to enter into the biosciences industry he must be efficient with the wet lab and the dry lab technique.

 

Specialized Tools for Applied Biology :

STAB is a rigorous module which trains students on the applicative part of various tools and there requirement in the industry , the course also acquaints you with the use of these tools in the fields of biotechnology , microbiology , life sciences etc.

 

Application of Our STAB in the Industry ?

Our STAB module are designed and validated by the professionals working in the core bioinformatics industry ,the course consists of all those tools which an student should be well equipped before entering into the industry and for getting a better placement .

 

Course Description :

The course trains you on 5 basic modules:

Module 1 : NCBI /BLAST
Module 2 : PCR and Primer Designing Tools
Module 3 : Gene Prediction and Related Softwares
Module 4 : Introduction to Chem informatics and Related Databases
Module 5 : Introduction to Systems Biology

Medium : Regular , 2 Months

    

Specialized Tools for Applied Biology - STAB

Below is a small description of the tools covered in the Biointelligence STAB course.

 

• SEQUENCE ANAYSIS

NCBI BLAST

Developed by National Center of Biotechnology Information
The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to study infer functional and evolutionary relationships between sequences as well as helps identify the members of gene.

 

• POLYMERASE CHAIN REACTION (PCR) AND PRIMER DESIGN TOOLS

Primer3

Developed by Whitehead_Institute and Howard Hughes Medical Institute
Primer3 is a widely used program for designing PCR primers (PCR = "Polymerase Chain Reaction"). PCR is an essential and ubiquitous tool in genetics and molecular biology. Primer3 can also design hybridization probes and sequencing primers. PCR is used for many different goals. Consequently, primer3 has many different input parameters that you control and that tell primer3 exactly what characteristics make good primers for your goals.

NetPrimer

Developed by PREMIER Biosoft International
NetPrimer combines the latest primer analysis algorithms with a web-based interface allowing the user to analyze primers over the Internet. The program eases quantitation of primers by calculating primer molecular weight and optical activity. To facilitate the selection of an optimal primer, each primer is given a rating based on the stability of its secondary structures.

 

• GENE PREDICTION

Gene finding typically refers to the area of computational biology that is concerned with algorithmically identifying stretches of sequence, usually genomic DNA, that are biologically functional. This especially includes protein-coding genes, but may also include other functional elements such as RNA genes and regulatory regions. Gene finding is one of the first and most important steps in understanding the genome of a species once it has been sequenced.

Gene Mark

Developed by Georgia Institute of Technology
GeneMark the first tool used for Gene Prediction. The Gene Mark algorithm uses species specific inhomogeneous Markov chain models of protein-coding DNA sequence as well as homogeneous Markov chain models of non-coding DNA. Parameters of the models are estimated from training sets of sequences of known type. The major step of the algorithm computes a posteriory probability of a sequence fragment to carry on a genetic code in one of six possible frames (including three frames in complementary DNA strand) or to be “non-coding”.

GenScan

Developed by Stanford University
GeneScan is a sophisticated software program that converts raw data to analyzed data through the application of a size standard, a matrix file, and specific parameter settings. GeneScan software sizes peaks using the internal size standard added to the sample prior to separation. GeneScan software is flexible, easy to use, and incorporates features that enable rapid and accurate analysis of data.

 

• SYSTEMS BIOLOGY

Cytoscape

Developed by National Center for Research Resources (NCRR) and the U.S. National Institute of General Medical Sciences (NIGMS)
Cytoscape is an open source bioinformatics software platform for visualizing molecular interaction networks and biological pathways and integrating these networks with annotations, gene expression profiles and other state data. Cytoscape core distribution provides a basic set of features for data integration and visualization. Additional features are available as plugins.

Cell Designer Developed by The Systems Biology Institute

Cell Designer is a structured diagram editor for drawing gene-regulatory and biochemical networks. Networks are drawn based on the process diagram, with graphical notation system proposed by Kitano, and are stored using the Systems Biology Markup Language (SBML), a standard for representing models of biochemical and gene-regulatory networks. Networks are able to link with simulation and other analysis packages through Systems Biology Workbench (SBW). By using CellDesigner, you can browse and modify existing SBML models with references to existing databases, simulate and view the dynamics through an intuitive graphical interface.

 

• CHEMINFORMATICS

Chem Bank

ChemBank is a public, web-based informatics environment created by the Broad Institute's Chemical Biology Program and funded in large part by the National Cancer Institute's Initiative for Chemical Genetics (ICG). This knowledge environment includes freely available data derived from small molecules and small-molecule screens, and resources for studying the data so that biological and medical insights can be gained. ChemBank is intended to guide chemists synthesizing novel compounds or libraries, to assist biologists searching for small molecules that perturb specific biological pathways, and to catalyze the process by which drug hunters discover new and effective medicines.

Drug Bank

The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information

PubChem

PubChem is organized as three linked databases within the NCBI's Entrez information retrieval system. These are PubChem Substance, PubChem Compound, and PubChem BioAssay. PubChem also provides a fast chemical structure similarity search tool.

 

Eligibility :

For enrolling into the course an individual with below mentioned qualification is acceptable ,
# Bachelors in Biotechnology , Microbiology, Bioinformatics , Life sciences, Biochemistry , Zoology , Botany and Related disciplines.
# Masters in Biotechnology , Microbiology, Bioinformatics , Life sciences, Biochemistry , Zoology , Botany, Genetic Engineering and Related disciplines.
# Mtech in Bioinformatics, Biotechnology and Disciplines

 

Contact Details :

Address : Biointelligence
First Floor Devdarshan Building
20/1 South Tukoganj , Opp. Sanghi Motors
A.B. Road , Palasia , Indore M.P.-452001

Desk Phone : 0731-4204793, 3260679
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Web: www.biointelligence.in